Survival Mode is a new mode introduced in the recent 3DS v1.3 update and Mobile v1.6 update, and unlocks after clearing Stage 150 - Mega Mewtwo. In this mode, the player can choose any four Support Pokémon they want and battle up to 50 stages in a row. It costs three Hearts to start the attempt, but the player can continue until they fail a stage. The player starts with 5 moves, but clearing a stage awards them several more moves.
Most stages in this mode choose a stage randomly from a set of stages, but some are fixed stages. Clearing certain milestone stages also awards certain Enhancements.
| Level | Possible Stages | First Reward | After Reward |
|---|---|---|---|
| 1 | Main Stages: Stages 1-5 | ||
| 2 | Main Stages: Stages 6-9 | ||
| 3 | Stage 10: Mega Audino | ||
| 4-5 | Main Stages: Stages 11-19 | ||
| 6 | Stage 20: Mega Kangaskhan | ||
| 7-9 | Main Stages: Stages 22-44 | ||
| 10 | Stage 30: Mega Sableye | Exp. Booster M | Exp. Booster S |
| 11 | Stage 45: Mega Slowbro | ||
| 12-14 | Main Stages: Stages 31-74 | ||
| 15 | Stage 103: Raichu | ||
| 16 | Main Stages: Stages 31-74 | ||
| 17 | Stage 90: Mega Mawile | ||
| 18-19 | Main Stages: Stages 76-89 | ||
| 20 | Stage 75: Mega Altaria | Exp. Booster L | 2 Exp. Booster S |
| 21-22 | Main Stages: Stages 1-74 | ||
| 23-26 | Main Stages: Stages 46-74 | ||
| 27 | Stage 60: Mega Lopunny | ||
| 28-29 | Main Stages: Stages 90-119 | ||
| 30 | Stage 120: Mega Glalie | Raise Max Level | 3 Exp. Booster S |
| 31 | Main Stages: Stages 1-104 | ||
| 32-33 | Main Stages: Stages 76-104 | ||
| 34 | Main Stages: Stages 129-131 | ||
| 35 | Main Stages: Stages 129-131 | Level Up | Exp. Booster M |
| 36 | Main Stages: Stages 129-131 | ||
| 37 | Main Stages: Stages 1-119 | ||
| 38-39 | Main Stages: Stages 76-119 | ||
| 40 | Stage 105: Mega Ampharos | Raise Max Level | 2 Exp. Booster M |
| 41 | Main Stages: Stages 1-134 | ||
| 42-44 | Main Stages: Stages 121-134 | ||
| 45 | Stage 135: Mega Gengar | Level Up | 3 Exp. Booster M |
| 46 | Main Stages: Stages 1-148 | ||
| 47-49 | Main Stages: Stages 136-148 | ||
| 50 | Stage 150: Mega Mewtwo Y | 3 Raise Max Level | Exp. Booster L |